The Prison Epistles were written during Paul’s imprisonment in Rome about 62-63 A.D. Each of these epistles were studied independently as material for teaching adult Sunday school classes. Each is word-by-word study of the text with a definition of its meaning derived from Bible dictionaries and commentaries. In effect, these are inductive studies: what does the text say, what does it mean and how is it to be applied to one’s life. I was doing a review of Paul’s three great missionary trips when I realized he had made at least four such trips and perhaps five. His fourth trip included the two years he spent in Roman confinement and his preparation of the epistles covered by this study. We have no biblical record of a possible fifth missionary trip, but tradition tells us that Paul was released in Rome in 63 A.D. and traveled widely visiting the churches he had helped found and perhaps even traveled to Spain. The introduction to this publication is a review of the details of this trip, the people he encountered, the public personalities he was privileged to witness to including kings, governors, and the elite of Rome’s military. It details the places visited, the hardships encountered and the impact of this saint’s witness for Christ.