"Application Security Program Guide - Building a Comprehensive Application and Product Security Program" is a comprehensive roadmap tailored for building effective application and product security programs. Designed for security leaders and teams, it offers strategic, practical advice for tackling complex security challenges and emphasizes risk reduction and mitigating vulnerabilities in applications. This guide starts with foundational security concepts, progressing to risk management, aligning security with software development lifecycles, and building skilled teams. It also explores Artificial Intelligence (AI) and Machine Learning (ML) security, cloud security, incident response, and the role of automation in application security. Concluding with metrics and maturity assessments, it provides a complete framework for enhancing application security programs.