An introduction to classical biostatistical methods in epidemiology
Biostatistical Methods in Epidemiology
provides an introduction to a wide range of methods used to analyze epidemiologic data, with a focus on nonregression techniques. The text includes an extensive discussion of measurement issues in epidemiology, especially confounding. Maximum likelihood, Mantel-Haenszel, and weighted least squares methods are presented for the analysis of closed cohort and case-control data. Kaplan-Meier and Poisson methods are described for the analysis of censored survival data. A justification for using odds ratio methods in case-control studies is provided. Standardization of rates is discussed and the construction of ordinary, multiple decrement and cause-deleted life tables is outlined. Sample size formulas are given for a range of epidemiologic study designs. The text ends with a brief overview of logistic and Cox regression. Other highlights include:
Many worked examples based on actual data
Discussion of exact methods
Recommendations for preferred methods
Extensive appendices and references
provides an excellent introduction to the subject for students, while also serving as a comprehensive reference for epidemiologists and other health professionals.
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