Teenage telepath Calliope O'Callahan must work very hard as a paid psychic to cover the cost of her mother's kidney transplant. Her talents come to the attention of the Psy Syndicate, an organization that teaches and tests talented people like her. She meets Chillian, a girl who can see when and how people die, Winston, a boy who can walk through dreams, Siobhan, a dowser, and many others. Amber Biggs' abduction is one of the cases Callie is assigned to along with several other psychics, but the police aren't doing anything to save the girl. Is Callie's psychic ability good enough to save Amber?