The inflammation of the nervous tissue is termed as neuroinflammation. It is generally regarded as a chronic inflammation. It is initiated as a response to infection, aging, toxic metabolites, traumatic brain injury, spinal cord injury or autoimmunity. Microglia are activated in response to such stimuli in the central nervous system. The class of proteins called cytokines regulate inflammation, cell signaling and other cell processes such as cell growth and survival. Neuroinflammation is strongly associated with several neurodegenerative diseases, such as Alzheimer’s disease, multiple sclerosis and Parkinson’s disease. Drug therapy and exercise are some potential treatment strategies for the management of neuroinflammation. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in neuroinflammation. It presents this complex subject in the most comprehensible and easy to understand language. This book, with its detailed analyses and data, will prove immensely beneficial to professionals and students involved in neurology at various levels.