This book is a cultural exploration of health and wellness, with a focus on impacts of Covid-19 on the population of India. The chapters in this book present original research, systematic reviews, theoretical and conceptual frameworks, encompassing multidisciplinary, inter- and intra-disciplinary fields of study, in the context of how culture and disease sufficiently unpack and inform each other. The book includes contributions from the social sciences and the humanities and analyses issues that range from smallpox to the history of vaccine, indigenous healing practices, the Macbeth paradigm, Zizekian encounters, mental asylum, and marginalised genders. Using the theme of intellectual interconnectedness in the times of self-isolation and social distancing, the book is a collaboration of critical thinkers who identify and visibilize the hidden global issues related to ‘disease’ and ‘health’ that have divided the world into narrow binaries – individual/society, poor/rich, proletariat/bourgeoisie, margin/centre, colonised/coloniser, servitude/liberty, powerless/powerful. By doing so, the book emphasises the potential of holistic wellness to improve human life and humanity across the globe. A novel contribution on the cultural factors that played an important role in contemporary times of Covid-19, this book will be of interest to researchers in the fields of Cultural Studies, Health and Society and South Asian Studies.