Sarcoma is a cancer which originates in the transformed cells of mesenchymal origin. All malignant tumors consisting of the cartilage, cancellous bone, muscle, fat, hematopoietic or vascular tissues are sarcomas. Askin’s tumor, malignant hemangioendothelioma, osteosarcoma, chondrosarcoma, malignant schwannoma, etc. are certain types of sarcomas. Surgery is commonly used in the treatment of sarcoma. Limb-sparing surgery is performed in extremity tumor cases. Along with surgery, chemotherapy and radiation therapy can also be used. Sarcomas in humans are quite rare, though it can affect people of all ages. Oncology is an upcoming field of science that has undergone rapid development over the past few decades. This book aims to shed light on some of the unexplored aspects of sarcoma and the recent researches in this condition. For all readers who are interested in sarcoma diagnosis and management, the case studies included in this book will serve as an excellent guide to develop a comprehensive understanding.