When a laboratory created human spliced with alien DNA escapes his government confines with plans to violently lay siege to all the Earth, it is up to six college students in Virginia to stop this vicious Demigod known as; Shemihazah. Cliff is a self-taught activist rallying against the Trans-Humanist agenda. When his friend Hugo, a government contracted geneticist, summons him to Washington, D.C to watch the dissection of the government's latest 'creation', the subject (Shemihazah) kills everyone in the building- and would have killed Cliff too if not for his accidental savior, ex-military and Chief NASA Security agent Victoria Harper. Vic and her brother Brandon take Cliff under their protection as they are forced to break into and steal secrets contained in the 'Shemihazah Files' from several government facilities. Shemihazah chases them across seven State lines and when he finally catches and viciously kills all three of them, he finds that the items he seeks (that can bring forth his destruction before his plans are finished) have been passed on to six Virginian college students embarking on a weekend trip into the Blue Ridge Mountains. Shemihazah tracks down the students and a battle for the lives of every living soul that walks the Earth ensues.