The aim of this book is to describe electrolyte disorders in a group of hospitalized HIV-infected patients in the city of Bamako. We conducted a retrospective analytical cross-sectional study in the infectious diseases department of the CHU du Point G, from 1 January 2011 to 31 December 2016. Our study parameters were ionogram results during hospitalisation. One hundred and twenty-six patients living with HIV who had a blood ionogram during hospitalisation were included. The mean natraemia value was 133.06±12.16 mmol/l and the mean kalaemia value was 3.89±1.15 mmol/l, with extremes of 83.00 and 166.00 mmol/l and 1.60 and 9.00 mmol/l respectively. The electrolyte disorders found were hyponatraemia (41.2%), hypokalaemia (12.7%), hypernatraemia (7.8%), hyperkalaemia (2.9%) and associated disorders (35.3%). Statistically significant associations were found between these disorders and certain events that occur frequently in HIV-infected patients. Electrolyte disorders are common in patients living with HIV.