Stroke is the second major cause of disability after dementia globally. In sub-Saharan Africa the incidence is increasing and occurring at even younger ages. Most stroke survivors return home after discharge and the burden of caring for them largely falls on their families and communities around them. These informal caregivers are directly affected by patients' illness and this can affect their health status. They are at higher risks of mental and physical illnesses. Caregivers experiencing strain are at a higher risk for mortality especially in elderly spouses. The identification of key factors that contribute to the stress of caregivers can help in designing intervention programs that enhance coping skills and improve overall care and wellbeing of the stroke survivors.