This book provides the readers with the global researches in chronic fatigue syndrome. Chronic fatigue syndrome (CFS) is the ordinary name for a collection of notably unbearable medicinal conditions characterized by constant exhaustion and other precise symptoms that last for a least of six months in adults. The fatigue is not due to physical exertion, not considerably comforted by rest, and is not caused by other medicinal situations. As sophisticated biomedical study methods are more and more practical to the research of CFS, it is certainly only a subject of time before biomarkers are identified, etiologies understood and remedies devised. This book acknowledges the actuality of CFS for patients with this disease and the significance of knowing the reasons, curing process and eventually a treatment. And while it is far from being a solution to CFS problems, it does showcase attempts to understand this complicated ailment with an underlying theme of considering CFS as a multisystem disease with its cause being an interplay of variety of reasons.