Kathryn Snyder's sister is married to Matt Larsen's brother. That fact does not make them the best of friends. The only thing they have in common is both are crazy about their eighteen month old niece, Zoë. They share the delight and responsibility of being Zoë's god-parents.When tragedy strikes and Zoë's parents are killed in a car wreck, Kathryn and Matt are named as Zoë's guardians. Can Kathryn balance the demands of the career she's always wanted with instant motherhood? Will Matt be able to adapt his independent way of life to care for a toddler? Somehow, Kathryn and Matt must not only deal with their individual issues but also work together and find common ground to become Zoë's "Guardian Angels."