Handbook of Synthetic Organic Chemistry, Second Edition updates and expands the author's popular 2007 work, Synthetic Organic Chemist's Companion. This new handbook provides valuable, practical guidance; incorporates corrections, and includes coverage on important topics, such as lyophylization, crystallization, precipitation, HPLC detectors, gases, and microwave reactions.The book maintains the useful organization of the author's earlier work, beginning with a basic overview and walking through every practical step of the process of organic synthesis, from reagents, solvents, and temperature control, to documentation, implementation, purification, and analytical methods for the product.From planning and setting up reactions, to recording them, the book provides insight and valuable guidance into every step of the process.- Contains practical information for every part of the process that are coupled with engaging, real-world examples- Presents useful guidance for conducting literature searches, handling and preparing reagents, working up the reaction, and identifying the product- Presents valuable coverage of conventional and microwave temperature control, paper and electronic research notebooks, eluent selection, Schlenk lines, purification methods and determination, chiral chromatography, chemical safety, and more