This study was to explore the impact of Covid-19 pandemic on fish sales in the Aboabo Market in the Tamale Metropolis. The data were collected from 57 fish sellers who play their trade in the Aboabo market using multi-stage sampling. Paired T-test was use to analyse the earnings of fish sellers before and during the Covid-19 pandemic. The results showed that 38.6, 35.1, 3.5 and 22.8% of respondent sold smoked-fish, fresh-fish, salted fish and frozen fish, respectively. The quantity of fish sold by majority (61.4%) of the fish sellers decreases during the pandemic compared to before the pandemic. A majority (57.9%) of fish sellers had their earnings reduced during the Covid-19 pandemic compared to before thepandemic (47.4%). The Covid-19 pandemic has affected the quantity of fish sold and have reduced the income of fish sellers in the Tamale Metropolis. This could compound issues of food security and livelihood of the fish sellers. The study recommends Philanthropies and donor agencies to design a financial support for the fish sellers to cushion them to resist against future pandemic.