Metabolic disease is a medical condition that occurs when abnormal chemical reactions in the body modify the normal metabolic process. It can result in affecting the ability of the cell to perform biochemical reactions. It includes the transport or processing of proteins, carbohydrates, or lipids. The metabolic disease consists of four kinds of symptoms- acute symptoms, late-onset acute symptoms, progressive general symptoms, and permanent symptoms. Most of the metabolic diseases are hereditary and occur when a defective gene causes an enzyme deficiency. Some kinds of metabolic diseases are acid-base imbalance, metabolic brain diseases, disorders of calcium metabolism, DNA repair- deficiency disorders, etc. The diagnosis of metabolic diseases can be done when symptoms appear with the help of specific blood and DNA tests. A metabolic disorder can be treated with the help of nutrition management. This book contains some path-breaking studies in the field of metabolic disease. This book aims to shed light on some of the unexplored aspects of metabolic diseases and the recent researches in this field. This book is a vital tool for all researching and studying this field.