This monograph studies the scientific and theoretical aspects of increasing the investment potential of economic sectors based on public-private partnership. The content and essence of the methodology for assessing the investment attractiveness of economic sectors on the basis of public-private partnership has been revealed on the scientific and methodological basis of the priority directions of ensuring and developing the socio-economic potential of the regions of our country. Also, through the analysis of statistical indicators of "Uzbekistan Railways" JSC, advanced foreign experiences aimed at increasing the activity of the investment environment of economic sectors on the basis of public-private partnership and the prospects of using it in the conditions of Uzbekistan were interpreted. The questions raised in the monograph, the results of the analysis and the conclusions drawn can be widely used by scientific researchers, graduate students of higher educational institutions and practitioners-specialists interested in this field.