This contributed volume contains a collection of articles on state-of-the-art developments on the construction of theoretical integral techniques and their application to specific problems in science and engineering. The chapters in this book are based on talks given at the Fifteenth International Conference on Integral Methods in Science and Engineering, held July 16-20, 2018 at the University of Brighton, UK, and are written by internationally recognized researchers. The topics addressed are wide ranging, and include: • Asymptotic analysis • Boundary-domain integral equations • Viscoplastic fluid flow • Stationary waves • Interior Neumann shape optimization • Self-configuring neural networks This collection will be of interest to researchers in applied mathematics, physics, and mechanical and electrical engineering, as well as graduate students in these disciplines and other professionals for whom integration is an essential tool.