This volume is dedicated to Harry Dym, a leading expert in operator theory, on the occasion of his sixtieth birthday. The book opens with an autobiographical sketch, a list of publications and a personal account of I. Gohberg on his collaboration with Harry Dym. The mathematical papers cover Krein space operator theory, Schur analysis and interpolation, several complex variables and Riemann surfaces, matrix theory, system theory, and differential equations and mathematical physics. The book is of interest to a wide audience of pure and applied mathematicians, electrical engineers and theoretical physicists.