Irritable bowel syndrome (IBS) refers to a condition that causes abdominal pain and bowel changes. The common symptoms of IBS include changes in bowel movements, bloating, stomach cramps, and frequent diarrhea or constipation. In menstruating women, IBS symptoms may be even worsen. People with IBS usually have a lower pain tolerance. The precise cause of IBS is unknown. Some of the factors that seem to play a role include severe infections, intestine muscle spasms, changes in gut microbiota, and early life stress. IBS can be diagnosed by performing a physical examination along with a review of the symptoms, family history, and medical history. The IBS treatment aims to alleviate the symptoms with the help of probiotics, dietary changes, counseling, and medicine. This book contains a detailed explanation of the various diagnostic and therapeutic techniques associated with irritable bowel syndrome. It aims to shed light on some of the unexplored aspects of this condition. A number of latest researches have been included to keep the readers up-to-date with the latest concepts with respect to this medical condition.