A microscopic parasite has crippled humanity with night terrors and paralyzing anxiety. In this world of increasing dystopia, hope yet remains in Karma City. But when mercenary drifter, Jameson Shoals, learns that a famous scientist has created a stronger parasite to kill the original, it isn't until the bodies litter the streets that he realizes the horrifying truth: the new parasite is a killer with a mind of its own, and upon dominating Patient Zero, this killer acquires legs, hands, and eyes. It falls upon Shoals and his partner, a deadly female mercenary, to stop PZ and his mob before they can overcome and supplant humankind.