Cancer is established as a consequence of the accumulation of chromosomal mutations and epigenetic alterations of the genes involved in the regulation of the cell cycle. Genes that undergo variations in their methylation pattern are more predisposed to mutations and loss of functionality. Epigenetic marks imprinted on cells exposed to physiological stress of cancer-free individuals are similar to those found in tumor cells in their early stages.
Cancer is established as a consequence of the accumulation of chromosomal mutations and epigenetic alterations of the genes involved in the regulation of the cell cycle. Genes that undergo variations in their methylation pattern are more predisposed to mutations and loss of functionality. Epigenetic marks imprinted on cells exposed to physiological stress of cancer-free individuals are similar to those found in tumor cells in their early stages.
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