Modelling biological systems is an applied scientific field which aims to analyze and stimulate various biological structures and functions using computational and mathematical techniques. This book elucidates the concepts and innovative methods around prospective developments with respect to modelling biological systems. The chapters included trace the progress of this field and highlight some of its key concepts such as modelling genomics and proteomics, modelling and simulation of biological networks, simulating drug interactions with biological systems, ecosystem modelling, etc. This book is an essential guide for both professionals and those who wish to pursue this discipline further.