This book investigates the effectiveness and adaptability of Motivational Interviewing in smoking cessation. The research highlights MI's flexibility, demonstrating its effectiveness when combined with various interventions, such as CBT, NRT, and health coaching, providing a tailored support system for individuals. Key findings indicate that MI significantly improves motivation and commitment to quitting smoking, establishing it as a potent tool in smoking cessation. The book explores various MI implementations, including MI counselling with semi-structured scripts, MET, MI integrated with the 5As intervention, and MI sessions supported by booster sessions or contingent payments. Innovative methods such as MI-style chatbots and MI combined with self-help resources are also examined, showcasing MI's broad applicability. MI not only boosts motivation and commitment but also reduces relapse rates and increases the success of smoking cessation programs. This comprehensive approach addresses both psychological and physiological aspects of addiction, contributing to broader public health goals by reducing smoking-related diseases.