This controlled study of Eastern Orthodox spiritual intervention in the treatment of depression and anxiety, conducted in an empirical manner, is a benchmark in the scientific examination of Orthodox psychotherapy and a pioneering step in a new area of practical and applied theology. With increased attention by scholars to the relationship between spirituality and science, religion and physical / mental health, and holistic views of the human being that bring together the body and the mind, or spirit, this book provides a framework in the establishment of cross-cultural dimensions to the study of science and spirituality and the holistic concept of humans and their environment. These dimensions are indispensable in the development of any global notion of research in science and religion.