taneous vascular sealing devices. The obvious liability in including these topics in the text is that some may not be adopted or practical for broad clinical application. In this regard, it is not our intent to rec­ ommend or promote the use of investigational endovascular methods before they are proven by appropriate clinical studies, but rather to provide a detailed assessment of potential advances. To accomplish this goal, we have made timely production and publication of this book a priority so that information presented is as current as possible. Rodney A. White, M.D. Thomas 1. Fogarty, M.D. Contents Preface to the Second Edition .......................... v Preface to the First Edition ............................ vii Contributors ............ . . . . . . . . . . . . . . . . . . . . . . . . . . . .. xiii PART I INTRODUCTION 1 Evolution of Endovascular Therapy: Diagnostics and Therapeutics ....................... 3 Thomas 1 Fogarty and Amitava Biswas 2 Pathophysiology of Vascular Disease ................. 11 Christopher K. Zarins and Seymour Glagov PART 11 COMPONENTS OF AN ENDOVASCULAR PRACTICE 3 Training and Credentialing in Endovascular Surgery ..... 33 G. Patrick Clagett and Kenneth E. McIntyre Ir.