Many of the natural products have been isolated and characterized from the actinobacteria, for example polyketides, phenazines, peptides, indolocarbarbazoles, and sterols. To explore new antibiotics from actinobacteria, several bioinformatics and synthetic biology tools were developed. This book covers basics to recent protocols for drug discovery from actinobacteria.
Features:
Discusses the benefits of production of antibiotics and enzymes from actinomycetes in a large scale
Covers the synthetic biology approach
Describes the strain improvement of actinobacteria
Gives information on basic isolation of actinobacteria and modern techniques
Covers the applications and metabolic engineering strategies of actinomycetes
This book will be helpful for the pharmaceutical industries and researchers to develop new antibiotics from actinobacteria and can be used in support of future research in drug discovery.