Over the past three decades there have been new developments in therapeutic drug design. In
Rational Drug Design: Methods and Prools,
expert researchers in the field detail many of the methodologies used to study rational drug design. These include methods such as virtual screening of chemical hits, rational lead discovery by high throughput screening, combinatorial and fragment based lead generation, peptide based drug discovery, and animal models of lead validation. Written in the highly successful
Methods in Molecular Biology™
series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory prools, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical,
Rational Drug Design: Methods and Prools
seeks to aid scientists in the further study of rational drug design and future drug discovery.