A goal of modern dentistry is to manage non-cavitated caries lesions non-invasively through remineralization in an attempt to prevent disease progression and improve aesthetics, strength and function. Minimal invasive dentistry's first basic principle is remineralization of the early caries lesion, advocating a biological approach rather than the surgical approach. It include usage and application of remineralizing agent to the tooth structure (enamel and dentin lesion) which control the demineralization/remineralization cycle, depending around the microenvironment around the tooth. Modern dentistry has aims to manage non-cavitated carious lesion noninvasively through remineralization in an attempt to prevent disease progression, and to improve form, function, strength and esthetics of teeth. This book aims to provide detailed yet simplified information on various aspects of remineralizing agents and a brief information about process of demineralization and remineralization.