In Modern medicine, Hypercholesterolemia is under dyslipidemia. It is the presence of high cholesterol level in the blood. Now days, Hypercholesterolemia is a dangerous problem among the people. To know the effectiveness of Cinnamomum zeylanicum and Cinnamomum tamala in the management of Hypercholesterolemia to study the etiology, pathogenesis and symptomatology of Hypercholesterolemia according to ayurveda and modern science. Total 30 patients of Hypercholesterolemia were treated with Bark powder of Cinnamomum zeylanicum and Cinnamomum tamala, 1gm twice a day for 3 months. The results were assessed in terms of clinical recovery, symptomatic relief, and assessment of Lipid profile.