In the opulent celestial capital of the Lofty Realm, the spoiled harvest goddess Sakuna lives in luxury, resting on her late parents' legacy. Meanwhile, in the Lowly Realm, a ruthless mountain bandit pursues desperate humans to a cliff's edge, where a bridge between realms suddenly appears, bringing Sakuna face-to-face with these “children of men.” Their clash causes a massive explosion that angers the celestial ruler, Lady Kamuhitsuki, who exiles them all to Hinoe Island—a mysterious land between earth and heavens once home to Sakuna’s parents—and tasks them with reclaiming the “Isle of Demons” from a monstrous horde. As the daughter of a warrior god and harvest goddess, Sakuna must rediscover her birthright by enduring the wild, battling monsters, and cultivating the land. By aiding their immortal protector, the banished humans may regain a lost purpose. Together, they must unite to tame both the soil and the demons of Hinoe Island.