Learning methods for the twenty-first century will include those which are student-centered, learning-focused, and digitally enhanced. Teaching will become learning management; the lecturer will become a learning guide, and students will become learning inventors. This book provides chapters describing a number of methods to be used in higher education in the twenty-first century. Some methods have been in existence for a period of time; others are literally at the front edge of development. Trying them out, piloting them, and experimenting with them for the benefit of the student is well worth the effort. It is best to be as prepared as possible for future changes rather than waiting to see what is going to happen. Those who try and are successful will be the leaders in learning management of the near future. In the digital world, being at the leading edge has definite advantages. No matter which method is used, it should focus on the student as learner with the faculty member as a learning guide. To survive in the twenty-first century, students will need to become continuous learners, developing with changes at an exponential velocity. Educators need to keep this critical concept in mind.