This book uncovers the current knowledge on entrepreneurial cultures and the development of entrepreneurial ecosystems between Asia and Europe. Broadening the scope spatially and conceptually, the book discusses the entrepreneurial ecosystems as a system and mediator in their cultural, political, and socio-economic settings in an interdisciplinary approach. This allows a clearer perspective on stakeholders' interaction, international collaboration and competition, power relations, and political influence. The various chapters in this edited volume cover the peculiarities and differences in Asia, Europe, and Eurasia with the New Silk Road (or Belt and Road Initiative) as the bridging component. The chapters, written for researchers and policy makers interested in Asian-European cooperation, also include discussions on economic systems, globalization, and regionalization, politics, cultures, and digitalization.