Jane Ann Rogers is 15 years old when she travels from Britain to America with her parents in 1852. They were hoping she would enjoy looking for gold in California so much that she would forget about dreaming how to paint portraits as she was. On their way by wagon, they are trapped in an avalanche and her parents are killed. Jane Ann is kept alive when a white buffalo cow settles across where she’s buried. She is saved by a small hunting party of young Sioux Lakota who take her to their Medicine Man (Grandfather) and his daughter (Rena) with whom she lives for over three years while her broken bones are mending. Chief Sitting Bull discovered that she has visions of White Buffalo Woman and he asks her to tell the people what she can about the white man coming to Sioux land. He named her Sioux Blessing Girl but she is afraid the people will not like what she says. She decides to run away and ends up a captive of a band of Crow renegades led by a white Cavalry officer.She is protected by Bear, a cousin of Red Cloud. She is rescued by Red Cloud, but later she must choose between Red Cloud and Bear. Her husband and child are killed after she has been kidnapped and taken to St. Louis. Jane Ann is rescued by an old friend who helps her get passage back to Indian territory. She finds her husband and son have been killed. She tracks their spirits to the sacred Black Hills where White Buffalo Woman helps convince her to release them to Spirit and return home to England.